To avoid Wrong-positive final results, the 99th percentile really should be used as the Slash-off worth for diagnosing acute myocardial infarction. The use of two cut-off values51,52 — one to outline infarction along with a second designation for unstable angina with some degree of myocardial necrosis — has become suggested.fifty one,fifty two The ESC/ACC joint committee felt this solution lacked a scientific foundation.fifty Offered the multiplicity of assays and The point that diverse assays and laboratories advocate various Slash-off values, the use of two Slice-off values would have markedly elevated the heterogeneity of diagnoses.
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Reprinted, with permission, from Eggers KM, Oldgren J, Nordenskjold A, et al. Diagnostic price of serial measurement of cardiac markers in people with upper body agony: limited price of introducing myoglobin to troponin I for exclusion of myocardial infarction. Am Coronary heart J
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